Nos offres de technologies

/Nos offres de technologies
Nos offres de technologies 2017-11-24T10:31:02+00:00

Vous trouverez ci-dessous un listing et une fiche descriptive synthétique des projets accompagnés par MATWIN parvenus jusqu’à l’audition devant le Board MATWIN sur les 5 dernières années. La fiche projet détaillée est accessible pour ceux qui ont souhaité la mettre en libre accès.

Téléchargement TypologieOrganisationPorteur de projetNom projetTitre du projetMots-clés
2017
Therapy and diagnosticInstitut de Cancérologie de l'Ouest CARTRON Pierre-FrançoisDNMT3A/ISGF3G : a biomarker for GBM patients stratification and a therapeutic targetTargeting glioblastoma cells via high-resolution epigenetic reprogrammingGlioblastoma, high-resolution epigenetic, sensitization, reprogramming, temozolomide, personalised medicine
2017
TherapyUniversité de Reims Champagne-ArdenneDEDIEU Stéphane / JEANNE AlbinTAX2Pre-clinical validation of a CD47/TSP-1 antagonist as a competing cyclic peptide (TAX2)TSP-1, CD47, immunomodulation, therapeutic peptide
2017
TherapyTelomiumKELLERMANN Guillaume TelomiumA second chance for telomerase reverse transcriptase in anticancer immunotherapyImmunotherapy, telomerase, cancer vaccine, ribonucleoprotein
2017
TherapyAtlantheraLE BOT Ronan12b80; The solution for bone cancersA new Small Molecule Drug Conjugate -targeting bone to cure primary bone cancer and secondary bone metastasesBone cancer, bisphosphonate, doxorubicin, vectorization, bone-targeted drug delivery, chemotherapy, antineoplastic
2017
TherapyPDC*line PharmaLEVY LaurentPDC*lungA therapeutic vaccine candidate for lung cancer based on a proprietary allogeneic cell line of Plasmacytoid Dendritic Cells (PDC*line)Immuno-oncology, Therapeutic cancer vaccine, Immune checkpoint inhibitors combination strategy (anti-PD-1 / anti-PD-L1), Advanced stage non-small cell lung cancer, Plasmacytoid dendritic cells, Allogeneic cell therapy, Scale-up and GMP manufacturing, Cost of good optimization, clinical PoC trial, Platform versatility (indications, tumor antigens, HLA), MoA exploration
2017
TherapyUniversity of Brest MIGNEN Olivier / RENAUDINEAU YvesSTIM-CLLSensing and Treating the IMmune calcium signal in Chronic Lymphocytic LeukemiaLymphoproliferation, chronic lymphocytic leukemia, calcium, alternative Ca,2+ entry pathway, immunotherapy, STIM1
2017
DiagnosticCentre de Recherche de Biochimie Macromoléculaire (CRBM)ROUX PierreISOSTEMp53 isoforms : a major prognostic marker of the metastasis riskTumor suppressor p53, alternative splicing, prognostic biomarker
2016
TherapyCRCM (Marseille)AURRAND-LIONS MichelTherapeutic inhibition of GRASP55/JAM-C pathway in Acute Myeloid Leukemia through protein/protein interaction inhibition (2P2I)...Adhesion, drug resistance, therapeutic target, chemotherapy
2016
TherapyCHRU (Dijon)BONNOTTE BernardHuman monocytes-derived suppressive cells: new cell therapy against GvHD...Human monocyte-derived suppressor cells, T lymphocytes, regulatory T cells, graft-versus-host disease, inflammation
2016
DiagnosticNOVAPTECH (Bordeaux)FAUSSILLON-LAVILLE MarineAptamers to MMP-9 for imaging and targeting tumors...Theranostic, diagnostic, Imaging, probe, multimodality, aptamer
2016
TherapyINSERM (Bordeaux)GROSSET ChristopheIdentification of oncogenes-targeting microRNAs for liver cancer therapy...MicroRNAs, Glypican-3, beta-catenin, Hepatocellular carcinoma, Hepatoblastoma
2016
TherapyAGV DiscoveryGUICHOU Jean-FrançoisERK Inhibitors for the treatment of RAF and RAS mutated cancers...Preclinical development, cancer, therapeutic innovation, drug candidate, kinase inhibitors, ERK2
NC
2016
DiagnosticDIAG2TEC - IGh (Montpellier)MOREAUX JérômeDefine assyas for precision medicine in haematological malignancies...Biomarker, Theranostics, Hematological malignancies, Cancer
2016
DiagnosticINSERM (Nice)RICCI Jean-EhrlandTheranostic of non-hodgkin B lymphomas...Metabolism, metabolic inhibitors, anti-CD20, DLBCL, glycolysis.
2015
TherapyInstitut de Biologie de LilleDELHEM NadiraProposition of a novel anti‐tumoral immunotherapy based on the neutralization of regulatory T‐cells activity with anti‐galectin 9 monoclonal antibodies...Cancer immunotherapy, humanized monoclonal antibodies, regulatory T-cells, galectin-9
2015
TherapyUniversité Paris DescartesFORGEZ PatriciaNeurotensin (NTS) immunotherapy and platinum responses in advanced lung cancer...Lung cancer, neurotensin, immunotherapy, cisplatin response
NC
2015
DiagnosisUniversité de NantesHERMOUET SylvieMultiplex infectious antigens micro-arrays for personalized in-vitro diagnosis of myeloma...In Vitro Diagnostics (IVD), myeloma, personalized medicine, infection
2015
DiagnosisUniversité de NiceHUEBER Anne-OdileDevelopment of phosphorylated-Fas-based biomarker for apoptotic and survival outcome of Fas signaling in malignant haematological and solid tumours for improved design of targeted anti-cancer therapies...Targeted anti-cancer Therapy, biomarker, tyrosine phosphorylation, antibodies, solid and liquid tumors, apoptosis
2015
TherapyOREGON TherapeuticsPITTY Marc-HenriInhibitors of protein disulfide isomerase against cancer...Oncology - Resistance - PDI - Small Molecule Targeted Therapy - First in Class
2015
Medical device / DiagnosisUniversité de LilleSALZET MichelGUIDED SURGERY OF CANCERS BY REAL-TIME MASS SPECTROMETRY :SPIDERMASS...Real Time Monitoring, Mass Spectrometry, in-vivo Diagnosis, guided surgery
2015
TherapyUniversité de ToursVANDIER ChristopheDevelopment of anti-metastatic drugs, inhibitors of SK3-based channel complex, in targeted cancer therapy...Anti-metastatic drugs, Potassium Channel, Amphiphilic compound, Ion channel inhibitor
2015
TherapySyndiviaWAGNER AlainBio Specific and bio Stable reagent for thiols ligation...Cancer therapeutics, Antibody-Drug Conjugates, Immunoconjugates, breast cancer, lymphoma
2014
TherapyUniversité de BordeauxBARTHELEMY PhilippeHybrid Nucleic Acid-Lipids for Cancer Therapy...nanomedicine, drug delivery, cancer, chemotherapy
2014
TherapyInstitut de Pharmacologie Moléculaire et Cellulaire, NiceBRAUD VéroniqueDevelopment of therapeutic monoclonal antibodies for the treatment of B cell non-Hodgkin’s lymphomas...Therapeutic antibodies, cancer, immunotherapy
2014
TherapyUniversité de ToulouseDEHARO EricSIMALIKALACTONE E: A NEW NATURAL PRODUCT ACTIVE IN VIVO AGAINST DRUG RESISTANT HUMAN TUMORS (MELANOMA, LEUKEMIA, AND OTHER MAPK DRIVEN CANCERS)...Simalikalactone, MAPK driven cancers, resistance, B-Raf V600E mutation
NC
2014
TherapyInstitut Gustave RoussyPACI AngeloNanoOxaza for cancer treatment...Oncology, Cancer, Nanoparticles, Oxazaphosphorines
2014
TherapyUniversité de NiceROCCHI StéphanePreclinical validation of new anti-melanoma compounds active against sentive and resistant cell lines...Melanoma, therapy, resistance, solid and liquid tumors, reticulum stress, autophagy
NC
2014
DiagnosticCentre Henri Becquerel, RouenRUMINY PhilippeMultiplexed test for chromosomal translocation detection...Cancer causing fusion genes, in-vitro diagnosis diagnosis kits, Multiplexing
2013
TherapyUniversité de NiceAUBERGER PatrickNew nucleoside analogs fr therapy of hematopoietic malignancies...Azacitidine / Resistance / Nucleoside Analogues / Acadesine/ Apoptosis /Autophagy
2013
TherapyInstitut des Neurosciences de MontpellierBAKALARA NorbertA new class of bioactive molecules targeting cancer (First therapeutic indication: glioblastoma)...Oncology, glioblastoma, drug discovery, glycomimetic
NC
2013
TherapyUniversité Aix-MarseilleCHAMES PatrickStimulation of NK and T cells mediated antitumor immunity of Her2 positive breast cancer..."breast cancer, NK, T lymphocytes, CD16, CD3, NKG2D, bispecific antibody
NC
2013
TherapyUniversité de RennesDIMANCHE-BOITREL Marie-ChristineDairy propionibacteria targeting TRAIL to kill colon cancer cells..."Probiotic, recombinant, colon cancer, apoptosis, targeting, TRAIL
2013
TherapyUniversité d'AngersEYER JoëlANTI-GLIOBLASTOMA PEPTIDE (AGP)...Glioblastoma, peptide, microtubule, cancer from the nervous system
2013
TherapyUniversité de BourgogneGARRIDO CarmenTargeting Hsp 110 for cancer therapy...Targeted therapy, Heat shock Protein 110, small molecules, peptide mimetics
NC
2013
TherapyUniversité de NantesGREGOIRE MarcOncovirotherapy and measles virus vaccine...Measles virus, cancer, vaccine, oncolytic, Immunity.
NC
2013
TherapyUniversité Aix-MarseilleIOVANNA JuanNovel triazole nucleoside compounds as anticancer drugs against pancreatic cancer..."pancreas cancer, triazole nucleosides, chemotherapy, anticancer drugs, drug resistance."